David Gallant from Boston marketing software company Hubspot attended HostingCon 2012 to learn more about DDoS protection. Photo credit: William Toll of ProfitBricks
Boston is recognized as one of the most active innovation communities in the country because it brings together exciting startups, renowned educational institutions, and established technology companies. All of these factors helped make HostingCon 2012, which was held in Boston back in July, the most successful HostingCon to date.
One of the biggest new contributors to its success was the event?s efforts to reach out to local tech and startup communities ? a benefit to both those local startups, and an interesting addition of some prospective users for the regular attendees of HostingCon.
?HostingCon touches so many aspects of our city from academia to commerce,? Tim Stansky, advisor to Mass Innovation Nights and a first-time HostingCon attendee says.
Mass Innovation Nights is a monthly meet-up where companies from IBM and VMware to what Stansky calls ?kitchen table startups? launch new products. So far, 400 products have launched through Mass Innovation Nights since the events started three and a half years ago.
?What HostingCon did well is they reached out to the local community. It is very easy for a tradeshow to take place in a city, and for the city to not even know about it,? Stansky says.
Reaching out to the local community in Boston helped HostingCon attract new attendees, and the mix of new and familiar faces in the hosting industry provided for some interesting networking opportunities.
Jim Spencer, founder of website design and Internet marketing firm JBS Partners, was able to meet his web hosting provider, HostDime, as well as a prospective partner, GlowTouch Technologies. Spencer says he walked away from HostingCon with new ideas for growing his business and expanding in ways he hadn?t thought of before, including offering merchant services.
?Lou Honick, CEO of Host Merchant Services, really opened my eyes to all of the potential services available in the aisles of the convention hall, services that I could offer my clients, including his merchant services,? Spencer says. ?I had not thought strategically about hosting services over the years because it is a secondary offering that is made possible by my primary offerings around website design and development as well as blog and website migrations and conversions.?
Other first-time HostingCon attendees had a very specific idea of what they wanted to take away from the conference.
?I attended HostingCon specifically to learn about security and DDoS protection solutions and hear stories of what others are using to protect their shared environments,? David Gallant, spec-ops at Hubspot says. ?Also, it was located right here in Boston so I was just a few minutes away on the subway.?
Based in Boston, Hubspot is an all-in-one marketing software that has helps customers across 46 countries attract more visitors to their websites, convert more of those visitors to leads and drive customer growth. Rebecca Corliss, Hubspot marketing manager, presented at HostingCon on how businesses can use inbound marketing and social media to drive leads.
?I have been spending a significant about my day here at HubSpot working on security and infrastructure issues, and I found all of the DDoS panels and presentations very informative,? Gallant says. ?The DDoS panel led by Jeffrey Lyon, CEO of Black Lotus, was close to home because issues that I have experienced were discussed among the panel of experts.?
David Sarvai, director of engineering for DSCI Corporation, a New England unified communications company, says he learned a lot from the panel discussions as well.
?The panel discussions which provided insight to how providers run their networks and expo floor were the favorite,? Sarvai says. ?DSCI has a technical nature which begins at the nuts-n-bolts of any technology, and having a firm understanding of vendor offerings and how other providers operate are key.?
HostingCon 2013 will be held in Austin, Texas, from June 17-19 at the Austin Convention Center.
About Nicole Henderson
Nicole Henderson writes full-time for the Web Host Industry Review where she covers daily news and features online, as well as in print. She has a bachelor of journalism from Ryerson University in Toronto, and has been writing for the WHIR since September 2010. You can find her on Twitter @NicoleHenderson.
Cancer vaccine Special Focus series published in Human Vaccines & ImmunotherapeuticsPublic release date: 27-Aug-2012 [ | E-mail | Share ]
Contact: Betsy Granger hv@landesbioscience.com Human Vaccines & Immunotherapeutics, Landes Bioscience
In the wake of new cancer immunotherapies finally coming of age, cancer researchers highlight gating factors in the success or failure of novel cancer vaccines
August 27, 2012 -- In one of the most comprehensive peer-reviewed discussions on cancer vaccines and immunotherapeutics, a Special Focus in the journal Human Vaccines & Immunotherapeutics provides a critical view on cancer vaccines and a discussion on best approaches for the future. From firsthand accounts of principal investigators involved in numerous failed cancer vaccine programs, including Oncophage and MVAX, to commentary from world experts in cancer vaccine development, authors in the Special Focus recount the mistakes of the past and provide an critical lens into the future of cancer vaccines with a potential for success.
Of special consideration is the technological advancement in Second Generation DNA sequencing technology that has resulted in the vast amount of genetic data of tumor cells gathered over the past few years. According to authors in the Special Focus, these data confirm that the degree of antigenic heterogeneity of tumor cells has been greatly underestimated. Tumors, once thought to be made of homogeneous collections of cells, are actually comprised of cells that carry an extreme diversity of antigens, the molecular signatures that are responsible for triggering immune response against cancer. This influences the important area of Antigen Discovery, a major criteria of vaccine formulation.
"Due in large part to genomic sequencing data, it has become quite clear that cancer is a heterogeneous disease and thus cannot be treated by homogeneous therapies. Many past cancer vaccine programs were based on the false premise of tumor homogeneity," said Michael G. Hanna, Jr., Ph.D., guest editor and contributor in the Special Focus series. "With all that we have learned at both the tumor genomic and immunotherapeutic levels, it is essential to reevaluate the antigen discovery process. The use of the patient's own tumor is the purest means to obtain a robust tumor-specific immune response."
The promise of triggering the immune system to engage a perpetual defense against resilient and hard-to-find cancer cells continues to prompt research. There are approximately 150 therapeutic cancer vaccines in clinical development. Despite past failures of cancer vaccines, new science continues to validate and support cancer vaccine technologies. In this Special Focus, authors outline weak clinical trial design, manufacturing issues relating to short shelf life and sterility of product, and failure to identify proper dose, schedule and route of administration among the key reasons why more cancer vaccines are not on the market today.
Ronald Ellis, Ph.D., Editor-in-Chief of Human Vaccines & Immunotherapeutics, said: "Despite the accumulation of sound science that continues to support cancer immunotherapy approaches, there are serious gaps in the cancer vaccine R&D pipeline. Some new cancer vaccine technologies that apply the lessons learned from many years of trials and tribulations are in late stages of clinical development and could lead to realization of the promise of cancer immunotherapy."
The Special Focus appearing in the August 2012 issue includes an introduction, five original papers and a guest editorial. Selected experts include: David Berd, M.D. (DB Consultants; Wyncote, PA, USA), Mike Cusnir, M.D. (Mount Sinai Comprehensive Cancer Center; Miami Beach, FL, USA), Isaiah Fidler, Ph.D. (University of Texas MD Anderson Cancer Center, Houston, TX, USA), Michael G. Hanna, Jr., Ph.D. (Vaccinogen Inc, Frederick, MD, USA), and Dirk Reitsma, M.D., and Austin Combest, Pharm.D. (PPD, Wilmington, NC, USA). Guest Editors include: Alex Kudrin, M.D., Ph.D. (Consultant in Pharmaceuticals Medicine, London, UK) and Michael G. Hanna, Jr., Ph.D. (Vaccinogen Inc, Frederick, MD, USA). This is the first of two special sections in the Cancer Commentary Series, the second will appear in the September 2012 issue.
###
About Human Vaccines & Immunotherapeutics
Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer's and addiction. Many of these vaccines should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines.
Human Vaccines & Immunotherapeutics provides such a forum. It is published in a format that is accessible to a wide international audience in the academic, industrial and public sectors.
Media Contact:
Betsy Granger
Managing Editor
Human Vaccines & Immunotherapeutics hv@landesbioscience.com
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Cancer vaccine Special Focus series published in Human Vaccines & ImmunotherapeuticsPublic release date: 27-Aug-2012 [ | E-mail | Share ]
Contact: Betsy Granger hv@landesbioscience.com Human Vaccines & Immunotherapeutics, Landes Bioscience
In the wake of new cancer immunotherapies finally coming of age, cancer researchers highlight gating factors in the success or failure of novel cancer vaccines
August 27, 2012 -- In one of the most comprehensive peer-reviewed discussions on cancer vaccines and immunotherapeutics, a Special Focus in the journal Human Vaccines & Immunotherapeutics provides a critical view on cancer vaccines and a discussion on best approaches for the future. From firsthand accounts of principal investigators involved in numerous failed cancer vaccine programs, including Oncophage and MVAX, to commentary from world experts in cancer vaccine development, authors in the Special Focus recount the mistakes of the past and provide an critical lens into the future of cancer vaccines with a potential for success.
Of special consideration is the technological advancement in Second Generation DNA sequencing technology that has resulted in the vast amount of genetic data of tumor cells gathered over the past few years. According to authors in the Special Focus, these data confirm that the degree of antigenic heterogeneity of tumor cells has been greatly underestimated. Tumors, once thought to be made of homogeneous collections of cells, are actually comprised of cells that carry an extreme diversity of antigens, the molecular signatures that are responsible for triggering immune response against cancer. This influences the important area of Antigen Discovery, a major criteria of vaccine formulation.
"Due in large part to genomic sequencing data, it has become quite clear that cancer is a heterogeneous disease and thus cannot be treated by homogeneous therapies. Many past cancer vaccine programs were based on the false premise of tumor homogeneity," said Michael G. Hanna, Jr., Ph.D., guest editor and contributor in the Special Focus series. "With all that we have learned at both the tumor genomic and immunotherapeutic levels, it is essential to reevaluate the antigen discovery process. The use of the patient's own tumor is the purest means to obtain a robust tumor-specific immune response."
The promise of triggering the immune system to engage a perpetual defense against resilient and hard-to-find cancer cells continues to prompt research. There are approximately 150 therapeutic cancer vaccines in clinical development. Despite past failures of cancer vaccines, new science continues to validate and support cancer vaccine technologies. In this Special Focus, authors outline weak clinical trial design, manufacturing issues relating to short shelf life and sterility of product, and failure to identify proper dose, schedule and route of administration among the key reasons why more cancer vaccines are not on the market today.
Ronald Ellis, Ph.D., Editor-in-Chief of Human Vaccines & Immunotherapeutics, said: "Despite the accumulation of sound science that continues to support cancer immunotherapy approaches, there are serious gaps in the cancer vaccine R&D pipeline. Some new cancer vaccine technologies that apply the lessons learned from many years of trials and tribulations are in late stages of clinical development and could lead to realization of the promise of cancer immunotherapy."
The Special Focus appearing in the August 2012 issue includes an introduction, five original papers and a guest editorial. Selected experts include: David Berd, M.D. (DB Consultants; Wyncote, PA, USA), Mike Cusnir, M.D. (Mount Sinai Comprehensive Cancer Center; Miami Beach, FL, USA), Isaiah Fidler, Ph.D. (University of Texas MD Anderson Cancer Center, Houston, TX, USA), Michael G. Hanna, Jr., Ph.D. (Vaccinogen Inc, Frederick, MD, USA), and Dirk Reitsma, M.D., and Austin Combest, Pharm.D. (PPD, Wilmington, NC, USA). Guest Editors include: Alex Kudrin, M.D., Ph.D. (Consultant in Pharmaceuticals Medicine, London, UK) and Michael G. Hanna, Jr., Ph.D. (Vaccinogen Inc, Frederick, MD, USA). This is the first of two special sections in the Cancer Commentary Series, the second will appear in the September 2012 issue.
###
About Human Vaccines & Immunotherapeutics
Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer's and addiction. Many of these vaccines should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines.
Human Vaccines & Immunotherapeutics provides such a forum. It is published in a format that is accessible to a wide international audience in the academic, industrial and public sectors.
Media Contact:
Betsy Granger
Managing Editor
Human Vaccines & Immunotherapeutics hv@landesbioscience.com
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Apparently, it?s time for my semi-annual blog update!
I?ve been focusing a bit more on work-work this year, and dialing it back on some of the writing and speaking. Not entirely, just gathering up my thoughts so that I can continue working on things that are interesting and relevant.
Writing:?I?ve continued to post?Scatter/Gather, Razorfish?s Content Strategy blog. And I also published some articles elsewhere this year.
Speaking:?This year I got more serious about scaling back on the public speaking. The?My?Presentations?page has been updated with info and links to recordings (when available). Here?s also a list of just the new ones:
Coming soon ? I?ll be co-presenting a workshop and giving a talk at?Content Strategy Forum 2012, Cape Town, South Africa, October 24-26, 2012
Attending: Even though I?m doing less speaking, I still love the inspiration of going to conferences. I also went to Confab, and soon I?ll be going to dconstruct and XOXO.
Other:?One other thing I?ve been up to ? I?m serving as Producer on a documentary that Jason Scott is shooting about DEFCON. Here?s a teaser trailer. There?s some other clips, teasers, and test footage on Jason?s YouTube channel.
Just because money is tight these days, it doesn?t mean you can?t throw a wonderful baby shower for your pregnant friends or family. It?s simply a matter of making certain choices, maybe some concessions and using your creativity.
Location:
Have it at someone?s home. Preferably not the Mom-to-Be so she doesn?t get too stressed out, but a close friend or family member will work. Also, consider having it at the church or temple they belong to. They sometimes let members use their facilities for free or for nominal fees. Lodges and firehouses also offer very friendly rates to both members and non-members.
Food:
Since you?re not going to a restaurant, that cost isn?t a concern. But you need to feed everyone and not go broke in the process. You can use a catering company; they may offer package deals depending on the number of attendees you are expecting with a variety of pricing options. There may be someone among the group who owns their own catering company or has a propensity for providing food for large gatherings that can offer you food at cost. And please don?t forget that ?pot luck? is no longer a dirty word. It encourages people to become more involved with the party and show off their specialties.
Decorations:
K.I.S.S. Mylar balloons look great, but they?re unreasonably expensive. Put up lots of colorful balloons around the room (blown up by generous party-preppers). Streamers and banners are inexpensive at most of the party stores. If you want to include flowers, don?t have a florist make individual pieces. Instead ask them for 3-5 large bouquets which you can then break down yourself. The cost difference is staggering. Disposable cameras on tables can also help ensure that special moments are captured during the excitement.
Baby Shower Favors:
Quite simply: make them. Go to a craft store and buy inexpensive vases or some other glass item. Fill them with colored M&M?s and attach a ribbon with the Mom-to-Be?s name and the date of the party. Fill a bag with candy or other baby-related items and put it into a ?diaper?, closed with a safety pin with the ?appropriate? color. Small, scented candles with stickers or ribbons are another option. Most party stores have an enormous collection of inexpensive baby shower related items that you can combine in a variety of ways.
A baby shower does not have to be an expensive affair to be a memorable one. Remember to have fun in the planning and that the most important thing is that the Mom-to-Be has a wonderful party that is well-suited for her style.
This entry was posted on Tuesday, August 28th, 2012 at 9:20 am and is filed under Baby Shower, Baby Shower Favors, Baby Shower Ideas. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.
In The Little Prince, by Antoine P Saint- Exupery. n nThat law which affects not just Ohio pre existing health problems, but all states in the united states, imposes restrictions on exclusion of coverage for pre- existing conditions, provides credit for prior medical health insurance coverage and a means to provide certificates regarding such prior [...]
Sorry, Readability was unable to parse this page for content. Source: http://www.submitarticles-free.com/home-and-family/babies-toddler/do-you-realize-the-value-of-choosing-the-right-toddler-swimwear/ toxoplasmosis farrah fawcett colon aarp shia labeouf gurkha fubar
The Life and Violent Times of Eli Gault By J. Lee Butts Berkley, July 2009 If a hard life makes harder men, then Eli Gault is cast-iron in boots. Raised by a merciless, drunken fire-and-brimstone preacher, young Eli avenged himself upon his pious pa. Then, after he took all the kind charity he could handle [...]
MAN Sports?Born 2 Perform?it?s now turned the corner on 8 weeks til the USA?s, the biggest show of my life. Last year, I came within 1 single point of winning my class and earning coveted IFBB Pro status. I?ve spent the last 40+ weeks focused on making the improvements to my physique to make sure [...]
Share With Friends: | | Politics ? Top Stories News, News Feeds and News via Feedzilla. Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/238808877?client_source=feed&format=rss new orleans weather sparkle sacagawea new hope baptist church associated press foster friess new orleans hornets
Some of the biggest names in politics will be missing from the stage during the Republican National Convention this week in Tampa, and that?s no accident. The Mitt Romney campaign is aiming to focus squarely on President Obama?s record and the GOP future rather than on polarizing figures and controversies from the past.
The idea is to portray a competent, forward-looking party?and that has translated into leaving out a recent president and vice president, some tea party stars, and most of the Republicans who only months ago were fighting Romney for the nomination. The absent former rivals include Rep. Michele Bachmann, who won the Iowa straw poll in 2011; former pizza magnate Herman Cain, who once led national polls during the primary race; Texas Gov. Rick Perry, viewed as a juggernaut before he ran; and retiring Rep. Ron Paul, who is getting a video tribute but no live address.
Also missing from the podium, and the convention as well: Former President George W. Bush and former Vice President Dick Cheney. Bush and Cheney represent a decade of GOP dominance that voters don?t remember fondly. Even Republicans have been highly critical of deficit spending and bailouts during the Bush-Cheney years.
The two decided separately not to attend. They probably realized the ramifications of showing up, said Al Cardenas, chairman of the American Conservative Union. ?The leaders of the party from the last decade agree it?s in the party?s best interest to move forward,? he said.
Almost all of these no-shows have national favorability ratings in the 20s and 30s. That includes former Alaska Gov. Sarah Palin, who made an electric convention debut four years ago as the GOP vice presidential pick but won?t be onstage this year. Her absence, along with that of Cain, Bachmann, Donald Trump, and other tea party favorites, has not gone unnoticed. The conservative group TheTeaParty.net has asked conservatives to sign a petition condemning convention organizers for what they call a blatant and outrageous attempt ?to silence TEA PARTY voices and ignore the historic success of the Tea Party since 2009.?
Convention organizers are clearly aiming for the preferred audience in a new National Journal Convention Insiders Poll, in which 71 percent of Republican Insiders said it was more important for the convention to appeal to swing voters. Only 22 percent said it was more important to energize the base. Perhaps even more relevant for GOP planners: In an NBC News/Wall Street Journal poll last month, only 25 percent of Americans said they supported the tea party; 65 percent said they did not.
(Some Democrats, of course, will also be notably absent in Charlotte next week, including former Vice President Al Gore and former presidential contender Michael Dukakis. But Bill Clinton will speak just before President Obama accepts his renomination. And in 2008, even after Hillary Rodham Clinton?s long, hard primary fight against Obama, both Clintons spoke at the convention in a show of party unity?after Obama had chosen another rival, Joe Biden, as his running mate.)
The GOP nomination fight was a free-for-all of charges and countercharges. ?It was a bruising primary, a roller-coaster primary where some very nasty words were exchanged,? said Ron Bonjean, a Republican strategist. For instance, Perry saying Romney had practiced ?vulture capitalism,? Gingrich?s never-ending complaints that Romney and his allies were buying the election, and former Sen. Rick Santorum?s assertion that Romney was ?the worst Republican in the country to put up against Obama.?
Bonjean said putting former rivals onstage would make them look hypocritical after all that. But Santorum nevertheless scored a speaking role this week, and Gingrich did as well. A revised schedule issued on Sunday shows him slotted for an appearance with his wife on Thursday night. The rest of Romney?s onetime competitors? No go.
Running a fitness centre doesn?t end in making people sweat with the exercises and routines you instruct them to complete. New fitness marketing techniques now make use of a more holistic approach which does not merely focus on physical activity, but on diet and nutrition as well.
Folks have the tendency to believe that consuming less is always the best option when hitting the gym, particularly when they are attempting to lose weight. Calorie-burning exercises are not signals to starve. These are in fact the times when our bodies require more food to get an uninterrupted flow of nutrients that are needed for greater metabolic demands. Starvation diets could cause intense physical exhaustion because you deprive your body of glucose to fuel its functions. The resulting fatigue disturbs normal day-to-day functions and dampen efforts in performing exercises. It also contributes to mood swings, body aches, drowsiness, intellectual declines, vitamin insufficiencies, and certain medical ailments.
A diet plan must be healthy and consistent while drawing an array of nutrients from the different food groups within caloric limits. Based on an individual?s fitness goals, diet and exercise should always complement each other. A nutrition plan low in carbohydrates, for instance, is not recommended for a person training for a marathon who runs many miles each day because his type of exercise burns more. Persons who lift weights for body building need food choices which are loaded with protein. Protein aids in building muscle mass and in muscle repair. Low-glycemic diets are for those who need to drop extra weight. Low-glycemic food options take a longer time to be absorbed compared to their high-glycemic counterparts, thus making a person feel full for a longer period and decreasing his inclination to overindulge. Low-fat, low-sodium, and low-cholesterol eating plans are also good for people who exercise to keep their hearts healthier.
Focusing on different aspects of your client?s health to make his individual fitness objectives more attainable is a holistic gym promotion strategy. Valuable customers will feel your guidance in all of their efforts. Having a nutrition specialist in your staff to take a seat and plan daily meals with gym members is a fantastic investment. Without the proper nutrients that allow the person to perform at his best, exercise efforts can remain futile. You may even put up a mini restaurant within your health club if you have extra space and resources so as customers may avail of pre-set and individualised meals to save them from the trouble of cooking by themselves.
This article was written by admin on August 26, 2012
David Gallant from Boston marketing software company Hubspot attended HostingCon 2012 to learn more about DDoS protection. Photo credit: William Toll of ProfitBricks
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Public release date: 27-Aug-2012
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